Rouet ,V, Meddahi-Pellé A, Miao Hua-Quan , Vlodavsky I , Caruelle J. P , Barritault D
Heparin-like synthetic polymers, named RGTAs, mimic biological effects of heparin in vitro. J. Bio Mater. Res. Published Online: 1 Jun 2006

*Corinne Lallam-Laroye, Quentin Escartin, Aude-Sophie Zlowodzki, Denis Barritault, Jean-Pierre Caruelle, Brigitte Baroukh, Jean-Louis Saffar, and Marie-Laure Colombier. Periodontitis destructions are restored by synthetic glycosaminoglycan mimetic J. Bio Mater. Res. 2006 79A,675-83.

*Garcia-Filipe S, Barbier-Chassefiere V, Alexakis C, Huet C, Ledoux D, Kerros ME, Petit E, Barritault D, Caruelle JP*, Kern P. RGTA OTR4120, a heparan sulfate mimetic is a possible long-term active agent to heal burned skin.” J. Bio Mater. Res. On line and 80A 75-84, 2007.

Barritault D, Caruelle JP. Regenerating agents (RGTAs): a new therapeutic approach
Ann Pharm Fr. 2006 Mar;64(2):135-44. Review. French.

*Rouet V, Hamma-Kourbali Y, Petit E, Panagopoulou P, Katsoris P, Barritault
D, Caruelle JP, Courty J. A synthetic glycosaminoglycan mimetic binds vascular endothelial growth factor and modulates angiogenesis.J Biol Chem. 2005 Jul 13.

Barbosa I, Morin C, Garcia S, Duchesnay A, Oudghir M, Jenniskens G, Miao HQ, Guimond S, Carpentier G, Cebrian J, Caruelle JP, van Kuppevelt T, Turnbull J, Martelly I, Papy-Garcia D. “A synthetic glycosaminoglycan mimetic (RGTA) modifies natural glycosaminoglycan species during myogenesis” J Cell Sci. 2005 Jan 1; 118(Pt 1):253-64.

*Alexakis C, Caruelle JP, Sezeur A, Cosnes J, Gendre JP, Mosnier H, Beaugerie L, Gallot D, Malafosse M, Barritault D, Kern P. “Reversal of abnormal collagen production in Crohn's disease intestinal biopsies treated with regenerating agents”. Gut. 2004 Jan; 53(1):85-90.

*Alexakis C, Mestries P, Garcia S, Petit E, Barbier V, Papy-Garcia D, Sagot MA, Barritault D, Caruelle JP, Kern P. “Structurally different RGTAs modulate collagen-type expression by cultured aortic smooth muscle cells via different pathways involving fibroblast growth factor-2 or transforming growth factor-beta1”. FASEB J. 2004 Jul; 18(10):1147-9. Epub 2004 May 7.

*Morvan FO, Baroukh B, Ledoux D, Caruelle JP, Barritault D, Godeau G, Saffar JL. “An engineered biopolymer prevents mucositis induced by 5-fluorouracil in hamsters”. Am J Pathol. 2004 Feb; 164(2):739-46.

*Escartin Q, Lallam-Laroye C, Baroukh B, Morvan FO, Caruelle JP, Godeau G, Barritault D, Saffar JL. “A new approach to treat tissue destruction in periodontitis with chemically modified dextran polymers”. FASEB J. 2003 Apr; 17(6):644-51.

Meddahi A, Alexakis C, Papy D, Caruelle JP, Barritault D. “Heparin-like polymer improved healing of gastric and colic ulceration”. J Biomed Mater Res. 2002 Jun 5; 60(3):497-501.

Meddahi A, Bree F, Papy-Garcia D, Gautron J, Barritault D, Caruelle JP. “Pharmacological studies of RGTA(11), a heparan sulfate mimetic polymer, efficient on muscle regeneration”. J Biomed Mater Res. 2002 Dec 15; 62(4):525-31.

*Alexakis C, Guettoufi A, Mestries P, Strup C, Mathe D, Barbaud C, Barritault D, Caruelle JP, Kern P. “Heparan mimetic regulates collagen expression and TGF-beta1 distribution in gamma-irradiated human intestinal smooth muscle cells”. FASEB J. 2001 Jul; 15(9):1546-54.

* Ledoux D, Papy-Garcia D, Escartin Q, Sagot MA, Cao Y, Barritault D, Courtois J, Hornebeck W, Caruelle JP. “Human plasmin enzymatic activity is inhibited by chemically modified dextrans”. J Biol Chem. 2000 Sep 22; 275(38):29383-90.

*Yamauchi H, Desgranges P, Lecerf L, Papy-Garcia D, Tournaire MC, Moczar M, Loisance D, Barritault D. “New agents for the treatment of infarcted myocardium”. FASEB J. 2000 (14): 2133-4.

*Desgranges P, Barbaud C, Caruelle JP, Barritault D, Gautron J. “A substituted dextran enhances muscle fiber survival and regeneration in ischemic and denervated rat EDL muscle”. FASEB J. 1999 Apr; 13(6):761-6.

*Albo D, Long C, Jhala N, Atkinson B, Granick MS, Wang T, Meddahi A, Barritault D, Solomon MP. “Modulation of cranial bone healing with a heparin-like dextran derivative”. J Craniofac Surg. 1996 Jan; 7(1):19-22.

Aamiri A, Butler-Browne GS, Martelly I, Barritault D, Gautron J. “Influence of a dextran derivative on myosin heavy chain expression during rat skeletal muscle regeneration”. Neurosci Lett. 1995 Dec 15; 201(3):243-6.

*Blanquaert F, Saffar JL, Colombier ML, Carpentier G, Barritault D, Caruelle JP “Heparan-like molecules induce the repair of skull defects”. Bone. 1995 Dec; 17(6):499-506.

*Aamiri A, Mobarek A, Carpentier G, Barritault D, Gautron J. “Effects of substituted dextran on reinnervation of a skeletal muscle in adult rats during regeneration” C R Acad Sci III. 1995 Oct; 318(10):1037-43. French.

*Gautron J, Kedzia C, Husmann I, Barritault D. “Acceleration of the regeneration of skeletal muscles in adult rats by dextran derivatives” C R Acad Sci III. 1995 Jun; 318(6):671-6. French.