Inflammatory and immune cells control “emergency” signals to repair the injury. These “emergency” repair signals are not tissue specific and the repair process is more focused on bridging wound openings rather than preserving tissue homeostasis.

 This “emergency” repair may leave marks, scars or fibrosis, all leading to a loss of tissue quality and functionality.

 Alternatively, this “emergency” repair may be only partially effective in healing the wound. In some cases, the wound becomes chronic, blocked in a persistent inflammatory cycle that can go on for years before healing.

Once the wound finally heals, the result may also be a fibrotic or scared tissue.