Rencontrez-nous à…
Toute l’actualité d’OTR3
Neuroprotection | News | RGTA technology
Paris, France, June 29, 2026 – OTR3, a biotechnology company, announces today that the primary endpoint was met in its clinical trial MATRISS II. MATRISS II investigated the efficacy and safety of OTR4132 administered intra-arterially immediately after successful endovascular thrombectomy, in patients with acute ischemic stroke. The MATRISS II study [...]
Latest Publications | News | RGTA technology
Potential of Heparan Sulphate Mimetics Integrated Into Collagen Scaffolds for Enhanced Skin Wound Healing Nancy Avila-Martinez1 | Roman Krymchenko1 | Merel Gansevoort1 | Maren Pfirrmann1 | Sofia Aparicio1 | Agnes Choppin2 | Franck Chiappini2 | Denis Barritault2 | Martijn Verdoes1,3 | Toin H. van Kuppevelt1 | Bouke K. H. L. [...]
Neuroprotection | News
OPTIMIZATION OF EXTRACELLULAR VESICLES-BASED THERAPY IN THE TREATMENT OF ISCHEMIC STROKE Poster Session on the Friday 25th of April at 4:30PM at ISEV Congress in Vienna Ons BEN HADJ HASSEN1, Sarah RAZAFINDRAKOTO2, Jérôme TOUTAIN1, Isis BLANCHARD1, Viktoriia IVANOVA1, Charlène RENOULT1,3, Xavier LAFFRAY4, Minh-Bao HUYNH4, Carole BRUNAUD1, Karim BORDJI1, Gael LE [...]
Neuroprotection | News
OTR3 has initiated its Phase 2 clinical trial for OTR4132, a novel neuroprotector designed to enhance functional recovery in acute ischemic stroke patients following thrombectomy. A first-in-human pilot study, MATRISS, was conducted across three centers in France, evaluating six escalating doses. The results were promising, demonstrating favorable safety and efficacy [...]
Cacipliq 20 | Media Publications | RGTA technology
Overview of 10 years of practice with CACIPLIQ20® matrix therapy as a healing agent for hard to heal wounds: Efficacy, cost-effectiveness and future perspectives Background: Chronic, non-healing wounds remain a major challenge for health care practitioners and for society in general, both in terms of the enormous economic burden [...]
Dermatology | Media Publications
Merel Gansevoort 1 , SabineWentholt 1, Gaia Li Vecchi 1, Marjolein de Vries 1, Elly M. M. Versteeg 1, Bouke K. H. L. Boekema 2,3 , Agnes Choppin 4, Denis Barritault 4, Franck Chiappini 4 , Toin H. van Kuppevelt 1 and Willeke F. Daamen 1,* Fibrosis after full-thickness wound [...]
Lungs/Poumons | Media Publications
Laurie Perdigon (1) , Manon Barthe (1) , Hanan Osman-Ponchet (1) , Agnes Choppin (2) , Franck Chiappini (2) Human precision-cut lung slices (hPCLS) are a promising ex vivo model for respiratory research. These thin, precisely-cut tissues, obtained from fresh lungs using a vibrating microtome, retain the native 3D architecture [...]
Lungs/Poumons | Media Publications
Manon Barthe (1) , Laurie Perdigon (1) , Hanan Osman-Ponchet (1) , Agnès Choppin (2) , Franck Chiapini (2) Pulmonary fibrosis is a progressive, restrictive lung disease characterized by scarring and stiffening of lung tissue, ultimately leading to respiratory failure. This condition is driven by the excessive proliferation and migration [...]
