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  • Gilbert Zakine, MD, PhD; Anne Perruisseau-Carrier, MD, PhD; Corinne Becker, MD; Frédéric Sedel, MD, PhD; Luc Téot, MD; and Denis Barritault, PhD Abstract Background: CACIPLIQ20 (OTR3, Paris, France) is a medical device used for the treatment of chronic skin ulcers. It contains a heparan sulfate mimetic that accelerates tissue [...]

    11 April 2023

  • OTR3 is proud to share a recent publication in the “Aesthetic Surgery Journal Open Forum” from the Oxford University Press concerning “a retrospective self-controlled study evaluating the Prophylactic Effects of our Medical Device Cacipliq 20 on Postsurgical scars.” https://doi.org/10.1093/asjof/ojad031 Aesthetic Surgery Journal Open Forum (ASJOF) is an international award-winning, peer-reviewed, [...]

    11 April 2023

  • OTR3 receives a state guaranteed loan amounting to € 0.5 m.

    25 August 2021

  • OTR3 appoints new management teams as the company planned to launch a second generation of RGTA® products.

    29 June 2021

  • Cacipliq 20® - Ischemic wound First Clinical Pilot Study on critical ischemic leg ulcers with Matrix Therapy ReGeneraTing Agent (RGTA ® ) technology P. DESGRANGES, T. LOUISSAINT, E. ALLAIRE, B. GODEAU, K. KICHENIN, J.- P. BECQUEMIN, D. BARRITAULT Patients with non-healing leg ulcers due to severe limb ischemia and [...]

    15 February 2019

  • Cacipliq 20® - Chronic wound Regenerating matrix-based therapy for chronic wound healing: a prospective within-subject pilot study Groah SL, Libin A, Spungen M, Nguyen KL, Woods E, Nabili M, Ramella-Roman J, Barritault D. The aim of this study was to determine whether a skin-specific bioengineered regenerating agent (RGTA) heparan [...]

    15 February 2019

  • Cacipliq 20® - Post radiation Unexpected healing of radiation-induced scalp lesions with OTR4120, an heparan sulfate mimetic Johan W VAN NECK ,Yolinde S. ZUIDEMA, Marijke SMULDERS, Kurt J. BALMUS Link : Here

    15 February 2019

  • Cacipliq 20® - Diabetic Foot Ulcer Matrix Protection Therapy in Diabetic Foot Ulcers: Pilot Study of CACIPLIQ20® INES SLIM (MD), HOUDA TAJOURI (MD), DENIS BARRITAULT (PHD), MAHA KACEM NJAH (MD), KOUSSAY ACH (MD), MOLKA CHADLI CHAIEB MD, LARBI CHAIEB (MD) We evaluated whether matrix protection therapy by Cacipliq 20® [...]

    15 February 2019